188438-05-3

Basic information

• Product Name: 3-[5-(3,4-DICHLORO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID
• Synonyms: CHEMBRDG-BB 5850247;ASISCHEM Y85892;AKOS BB-8394;3-[5-(3,4-DICHLORO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID;RARECHEM AL BK 0810;(2E)-3-[5-(3,4-DICHLOROPHENYL)-2-FURYL]ACRYLIC ACID;OTAVA-BB 0117392214;ZERENEX ZX008924
• CAS NO: 188438-05-3
• Molecular Formula: C13H8Cl2O3
• Molecular Weight: 283.11
• Mol File: 188438-05-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 446.7°C at 760 mmHg
• Flash Point: 224°C
• Appearance: /
• Density: 1.436g/cm³
• Vapor Pressure: 9.18E-09mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: 3-[5-(3,4-DICHLORO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[5-(3,4-DICHLORO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID(188438-05-3)
• EPA Substance Registry System: 3-[5-(3,4-DICHLORO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID(188438-05-3)

Safety Data

• Hazardous Substances Data: 188438-05-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H8Cl2O3/c14-10-4-1-8(7-11(10)15)12-5-2-9(18-12)3-6-13(16)17/h1-7H,(H,16,17)/b6-3+

Upstream product

• 141-82-2 malonic acid 
• 52130-34-4 5-(3,4-dichlorophenyl)furfural 

Relevant articles and documents

Synthesis of 2-arylfuro[3,2-c]pyridines and their derivatives

A series of 2-arylfuro[3,2-c]pyridines was synthesized. 3-(5-Aryl-2-furyl)propenoic acids 1a-1h were converted to the acid azides 2a-2h, which in turn were cyclized to give 2-arylfuro[3,2-c]pyridine-4(5H)-ones 4a-4h by heating in Dowtherm. The pyridones 4a-4f were aromatized with phosphorus oxychloride to the 2-aryl-4-chlorofuro[3,2-c]pyridines 5a-5f, which were reduced with zinc and acetic acid to the title compounds 6a-6f. Reacted with phosphorus(V) sulfide, the pyridones 4a-4f yielded the corresponding thiones 7a-7f.