18852-53-4

Basic information

• Product Name: 1(3H)-Isobenzofuranone, 3-chloro-3-phenyl-
• CAS NO: 18852-53-4
• Molecular Formula: C14H9ClO2
• Molecular Weight: 244.677
• Mol File: 18852-53-4.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: 1(3H)-Isobenzofuranone, 3-chloro-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(3H)-Isobenzofuranone, 3-chloro-3-phenyl-(18852-53-4)
• EPA Substance Registry System: 1(3H)-Isobenzofuranone, 3-chloro-3-phenyl-(18852-53-4)

Safety Data

• Hazardous Substances Data: 18852-53-4(Hazardous Substances Data)

Usage

Class

Coumarins

Biological activities

Anti-inflammatory, antimicrobial, and anticancer properties

Applications

a. Drug discovery and development
b. Starting material in the synthesis of pharmaceuticals and agrochemicals

Structure

A derivative of coumarin with a chlorine atom at the 3-position and a phenyl group also at the 3-position

Pharmacological and biological effects

Studied for its potential effects on various biological processes and diseases

Natural occurrence

Part of the class of coumarins, which includes both natural and synthetic compounds

Stability

Relatively stable under normal conditions

Solubility

Soluble in organic solvents such as ethanol, methanol, and acetone

Reactivity

Can undergo various chemical reactions, such as substitution and condensation, to form new compounds

Safety and handling

Handle with care, as it may have potential toxic effects and should be stored in a well-ventilated area, away from heat and moisture.

Upstream product

• 85-52-9 2-Benzoylbenzoic acid 
• 7719-09-7 thionyl chloride 

Downstream Products

• 40825-12-5 Phenyl 2-benzoylbenzoate 
• 5471-75-0 3-phenoxy-3-phenyl-phthalide 
• 31802-10-5 (2-benzoylphenyl)(morpholino)methanone 
• 84538-58-9 3-Phenyl-3-(1-imidazolyl)-1(3H)-isobenzofuranone 
• 7335-63-9 3-methoxy-3-phenyl-phthalide 
• 79984-95-5 N-butyl N-methyl O-benzoylbenzamide 
• 136664-86-3 2,5-bis(o-benzoylbenzoyldioxy)-2,5-dimethylhexane 
• 136664-87-4 2,5-bis(o-benzoylbenzoyldioxy)-2,5-dimethyl-3-hexyne 
• 49701-18-0 2,5-bis<(1-phenyl-3-oxo-1,3-dihydro-1-isobenzofuranyl)dioxy>-2,5-dimethyl-3-hexyne 
• 7498-89-7 3-Ethoxy-3-phenyl-phthalid 
• 134563-37-4 (N-Cyanomethyl)-(N-isopropyl)-2-benzoylbenzamid 
• 137537-41-8 2-Benzoyl-N-butyl-N-cyanomethyl-benzamide 
• 137537-42-9 2-Benzoyl-N-cyanomethyl-N-cyclohexyl-benzamide 
• 137537-26-9 3-<(N-Cyanomethyl)-(N-phenyl)-amino>-3-phenyl-isobenzofuran-1-on 

Relevant articles and documents

A facile synthesis of novel cyclic esters of γ-keto acid derivatives by heck coupling reaction

γ-Keto acids and esters are highly useful compounds in organic synthesis, because a number of five-membered carbocycles and various other heterocycles can be readily obtained from them. A number of γ-keto acids derivatives have been synthesized with high

Relay catalysis using a rhodium complex/chiral Bronsted acid binary system: Enantioselective reduction of a carbonyl ylide as the reactive intermediate

Pass the baton: A one-pot relay catalysis for a carbonyl ylide formation/enantioselective reduction sequence using a dirhodium(II) tetracarboxylate and chiral phosphoric acid catalyst system is described. The four-step transformation involves a rhodium ca

High-purity 2 - (benzoyl) benzoyl chloride synthesis method

The invention discloses a method for synthesizing 2 - (benzoyl) benzoyl chloride method, comprises the following steps: (1) under the action of a catalyst, the O benzoyl benzoic acid and thionyl chloride takes acylation reaction, the preparation of 3 - ch