188530-96-3Relevant articles and documents
COMPOUNDS TO TREAT AMYLOIDOSIS AND PREVENT DEATH OF BETA-CELLS IN TYPE 2 DIABETES MELLITUS
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Page/Page column 52, (2010/11/24)
The invention discloses aromatic amides and sulfonates to treat or prevent type 2 diabetes mellitus (T2DM), the pathological consequences of T2DM, to inhibit amyloidosis or to prevent death of β-cells of the pancreas.
Synthesis and Reactions of 3-(Nosyloxy)-2-keto Esters
Hoffman, Robert V.,Catherine Johnson,Okonya, John F.
, p. 2458 - 2465 (2007/10/03)
A series of 3-(nosyloxy)-2-keto esters 7a-j were prepared from the corresponding α-keto esters by conversion to the trimethylsilyl enol ether and reaction with p-nitrobenzenesulfonyl peroxide. Conversion of these materials to 1,2,3-trifunctionalized compounds is described, and comparison of their properties with isomeric 2-(nosyloxy)-3-keto esters is discussed.