18854-01-8 Usage
Uses
Used in Agriculture:
ISOXATHION is used as a pesticide for controlling sucking pests, leaf miners, and some chewing pests in a variety of fruit, vegetables, and ornamental plants. Its application helps protect crops from damage caused by these pests, ensuring healthier and more productive plants.
Metabolic pathway
The principal route of isoxathion metabolism in soil, plants and mammals
is by hydrolysis, probably via the oxon to 3-hydroxy-5-phenylisoxazole
which is rapidly conjugated in both plants and rats. In soils, and to a
lesser extent in plants and mammals, further metabolism of 3-hydroxy-
5-phenylisoxazole proceeds via opening of the isoxazole ring to give
various metabolites of which benzoic acid is one of the more important.
De-ethylation of the phosphate moiety has not been observed.
Metabolism
The principal degradation route of isoxathion in animals,
plants, and soil is cleavage of P?O-isoxazole through
oxidative desulfuration to the oxon followed by hydrolysis
to 3-hydroxy-5-phenylisoxazole, which is conjugated in
both plants and rats.
Toxicity evaluation
The acute oral LD50 for rats is 112 mg/kg. NOEL
(2 yr) for rats is 1.2 mg/kg b.w. DT50 in soil is 9–40 d.
Degradation
Isoxathion is unstable to alkalis (PM). The hydrolysis product, 3-hydroxy-
5-phenylisoxazole (2), yielded 5-phenyl-3H-oxazolin-2-one (3) as the
major photoproduct via a photolytic rearrangement (Nakagawa et al.,1974).
Check Digit Verification of cas no
The CAS Registry Mumber 18854-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,8,5 and 4 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18854-01:
(7*1)+(6*8)+(5*8)+(4*5)+(3*4)+(2*0)+(1*1)=128
128 % 10 = 8
So 18854-01-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H16NO4PS/c1-3-15-19(20,16-4-2)18-13-10-12(17-14-13)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3
18854-01-8Relevant academic research and scientific papers
Condensation products
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, (2008/06/13)
Formamidine compounds of the formula EQU1 or WHEREIN R1 represents a substituted or unsubstituted phenyl radical, R2 represents hydroogen, alkyl, alkenyl or alkinyl and R3 represents acyl their manufacture and their use in pest control.
