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Usage

Uses

Used in Pharmaceutical Industry:
3-(Isocyanomethyl)benzyl-isocyanide is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form complex chemical structures, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
3-(ISOCYANOMETHYL)BENZYL-ISOCYANIDE is utilized as a building block in the production of agrochemicals, where its reactivity and ability to form complex structures are employed to create effective and targeted agricultural products.
Used in Organic Synthesis:
3-(Isocyanomethyl)benzyl-isocyanide is used as a versatile reagent in organic synthesis processes, enabling the creation of a wide range of organic compounds for various applications across different industries.

Upstream product

• 59276-03-8 N,N'-(1,3-phenylenebis(methylene))diformamide 
• 1477-55-0 1,3-di(aminomethyl)benzene 

Downstream Products

• 1034473-44-3 C₅₄H₇₂N₆O₁₄ 
• 1620164-77-3 1,3-phenylenebis[methylene(aminomethylidenebisphosphonic)] acid 
• 1620164-70-6 octaethyl 1,3-phenylenebis[methylene(aminomethylidenebisphosphonate)] 

Relevant academic research and scientific papers

Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein–Protein Interactions

Stapled peptides are chemical entities in-between biologics and small molecules, which have proven to be the solution to high affinity protein–protein interaction antagonism, while keeping control over pharmacological performance such as stability and mem

Synthesis and antiproliferative activity of aromatic and aliphatic bis[aminomethylidene(bisphosphonic)] acids

A series of aromatic and aliphatic bis[aminomethylidene(bisphosphonic)] acids was synthesized in the reaction of triethylphosphite with isonitriles followed by hydrolysis or dealkylation. The in vitro anti-proliferative effect of all synthesized tetraphosphonic acids against MCF-7 breast cancer cells, J774E macrophages and HL-60 promyelocytic leukemia cells was determined. Three aromatic derivatives (5a, 5f and 5j) showed a similar or higher anti-proliferative activity than zoledronic acid.

Rapid generation of macrocycles with natural-product-like side chains by multiple multicomponent macrocyclizations (MiBs)

A small parallel library of peptoid macrocycles with natural-product- derived side chains of biological importance was produced by Ugi-type multiple multicomponent macrocyclizations including bifunctional building blocks (Ugi-MiBs). Diverse exocyclic elements of high relevance in natural recognition processes, i.e., all functional amino acid residues (e.g., Cys, Arg, His, Trp) and even sugar moieties, can be introduced in a one-pot process into different types of peptoid-containing macrocyclic skeletons. This is exemplified by the use of a diamine/diisocyanide combination of Ugi-MiBs and N-protected α-amino acids or carboxy-functionalized carbohydrates as source for the natural-product-like exocyclic elements. Employed as the acid components of the multiple Ugi reactions, they appear as N-amide substituents on the macrocyclic cores. The use of different diamines and diisocyanides allows an easy variation of the N- to C-directionality and therefore of the position of the exocyclic elements. The Royal Society of Chemistry.