188540-85-4

Basic information

• Product Name: (R)-2-acetoxy-4-oxo-4-phenylbutyric acid
• Synonyms: (R)-2-acetoxy-4-oxo-4-phenylbutyric acid
• CAS NO: 188540-85-4
• Molecular Weight: 236.224
• Mol File: 188540-85-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-acetoxy-4-oxo-4-phenylbutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-acetoxy-4-oxo-4-phenylbutyric acid(188540-85-4)
• EPA Substance Registry System: (R)-2-acetoxy-4-oxo-4-phenylbutyric acid(188540-85-4)

Safety Data

• Hazardous Substances Data: 188540-85-4(Hazardous Substances Data)

Upstream product

• 14189-99-2 (R)-(+)-2-acetoxysuccinic anhydride 

Downstream Products

• 117017-04-6 (R)-2-acetoxy-4-phenylbutanoic acid 
• 90315-82-5 ethyl (R)-2-hydroxy-4-phenylbutyrate 

Relevant articles and documents

Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester

Provided is an industrially useful process for producing an optically active 2-hydroxy-4-arylbutyric acid or its ester. An optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4-arylbutyric acid. The 2-acyloxy-4-oxo-4-arylbutyric acid is converted to an optically active 2-acyloxy-4-arylbutyric acid through catalytic reduction. The 2-acyloxy-4-arylbutyric acid is hydrolyzed in the presence of an acid or an alkali to produce an optically active 2-hydroxy-4-arylbutyric acid. The 2-hydroxy-4-arylbutyric acid is reacted with an alcohol in the presence of an acid to produce an optically active 2-hydroxy-4-arylbutyric acid ester.