188549-20-4Relevant academic research and scientific papers
The first synthesis of some spiro[2,3-dihydro-2,2-dimethylbenzofuran-3,1'- cyclopropanes] through, Mo(CO)6 catalyzed, one pot claisen rearrangement-cyclization reaction of 2-cyclopropylidene-aryloxy alkanes
Bernard, Angela M.,Piras, Pier P.
, p. 585 - 586 (2007/10/03)
Mo(CO)6 effectively transforms the cyclopropylidene aryloxy derivatives 2a-e,g into the previously unknown spiro[2,3-dihydro-2,2- dimethylbenzofuran-3,1'-cyclopropanes] 3a-e,g.
Palladium (0) catalyzed nucleophilic substitution on 2-cyclopropylidene-phenoxy ethanes
Bernard, Angela M.,Piras, Pier P.
, p. 709 - 723 (2007/10/03)
2-cyclopropylidene-phenoxy ethanes 5, 2-substituted with alkyl, aryl or heterocyclic groups are readily obtained in high yields by the Wittig reaction of the easily accessible α-phenoxy etanones 4 with (3-bromo propyl) triphenylphosphonium bromide. They react with complete regioselectivity in palladium (0) catalyzed nucleophilic substitutions with a series of soft carbon nucleophiles giving an easy entry to 5,6-methanoamino acids.
