188607-29-6

Basic information

• Product Name: 1-[2-(Hydroxymethyl)-6,11-dihydrodibenzo[b,e]oxepin-11-yl]-4-phenylpiperidin-4-ol
• Synonyms: KF-24705
• CAS NO: 188607-29-6
• Molecular Formula: C₂₆H₂₇NO₃
• Molecular Weight: 401.50999
• Mol File: 188607-29-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[2-(Hydroxymethyl)-6,11-dihydrodibenzo[b,e]oxepin-11-yl]-4-phenylpiperidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(Hydroxymethyl)-6,11-dihydrodibenzo[b,e]oxepin-11-yl]-4-phenylpiperidin-4-ol(188607-29-6)
• EPA Substance Registry System: 1-[2-(Hydroxymethyl)-6,11-dihydrodibenzo[b,e]oxepin-11-yl]-4-phenylpiperidin-4-ol(188607-29-6)

Safety Data

• Hazardous Substances Data: 188607-29-6(Hazardous Substances Data)

Upstream product

• 188607-23-0 Methyl 11-(4-hydroxy-4-phenylpiperidine-1-yl)-6,11-dihydrodibenzo[b,e] oxepine-2-carboxylate 

Downstream Products

• 188607-30-9 [11-(4-Hydroxy-4-phenylpiperidine-1-yl)-6,11-dihydrodibenzo[b,e] oxepine-2-yl]carbaldehyde 

Relevant articles and documents

Phenylpiperidine derivative

PCT No. PCT/JP96/02589 Sec. 371 Date Mar. 13, 1998 Sec. 102(e) Date Mar. 13, 1998 PCT Filed Sep. 11, 1996 PCT Pub. No. WO97/10213 PCT Pub. Date Mar. 20, 1997A phenylpiperidine derivative or pharmaceutical acceptable salt thereof represented by formula (I): wherein X represents CH or N; Y-Z represents CH2-O, CH2-S, CH2-CH2, CH=CH or CONR5 (wherein R5 represents hydrogen or lower alkyl); R1 represents hydrogen, lower alkyl, halogen, lower alkoxy or trifluoromethyl; and R2, R3 and R4 are the same or different and each represents hydrogen, lower alkyl or QR6 (wherein Q represents a single bond or lower alkylene, and R6 represents hydroxy, lower alkoxyalkoxy, lower alkoxy, lower alkylthio, nitro, halogen, lower alkanoyloxy, lower alkoxycarbonyl, lower alkanoyl or carboxyl). The present invention provides novel phenylpiperidine derivatives useful as analgesics.