188679-10-9Relevant academic research and scientific papers
3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
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Page/Page column 33, (2010/02/17)
The invention relates to 3-aza-bicyclo[3.1.0]hexane derivatives of formula (I) wherein A, B, n, X, and R1 are as described in the description, and salts thereof, and their use as orexin receptor antagonists.
3-HETEROARYL (AMINO OR AMIDO)-1-(BIPHENYL OR PHENYLTHIAZOLYL) CARBONYLPIPERIDINE DERIVATIVES AS OREXIN RECEPTOR INHIBITORS
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Page/Page column 12, (2010/04/23)
The invention relates to piperidine compounds of formula (I) wherein X-R1 represents —N(H)-pyrimidinyl, wherein said pyrimidinyl is unsubstituted or mono-substituted wherein the substituent is selected from (C1-4)alkyl or halogen, or
AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS
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Page/Page column 36, (2010/09/07)
The invention relates to novel azetidine compounds of formula (I), wherein R1, R2, and X are as described in the description and their use as orexin receptor antagonists.
3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES
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Page/Page column 65, (2008/06/13)
The invention relates to 3-aza-bicyclo[3.1.0]hexane derivatives of formula (I) wherein A, B, n, X, and R1 are as described in the description, and salts thereof, and their use as orexin receptor antagonists.
PIPERIDINE COMPOUNDS
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Page/Page column 25, (2008/12/06)
The invention relates to piperidine compounds of formula (I) wherein X-R1 represents -N(H)-pyrimidinyl, wherein said pyrimidinyl is unsubstituted or mono-substituted wherein the substituent is selected from (C1-4)alkyl or halogen, or
Azole-phenyl urea derivatives as ACAT inhibitors and their production
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, (2008/06/13)
The present invention relates to azole-phenyl urea derivatives represented by the general formula (I): [wherein each of R1, R2and R3is H, halogen, C1-8alkyl or the like, and A is a group represented by the formula (i) or (ii): (wherein R4, R5, R6and X are as defined in the specification.)] and a pharmacologically acceptable salt thereof, which have ACAT-inhibitory activity and are useful as a prophylactic and therapeutic agent for hypercholesterolemia, atherosclerosis and various diseases caused by them; a process for producing said derivative; and an ACAT inhibitor containing said derivative or salt as an active ingredient.
