188712-75-6Relevant articles and documents
Artificial photosynthesis of methanol from carbon dioxide and water via a Nile red-embedded TiO2 photocathode
Jia, Yongjian,Xu, Yanjie,Nie, Rong,Chen, Fengjuan,Zhu, Zhenping,Wang, Jianguo,Jing, Huanwang
, p. 5495 - 5501 (2017)
The conversion of carbon dioxide into useful chemicals is a prospective strategy for alleviating the greenhouse effect and the depletion of energy. Herein, we report an artificial photosynthetic system composed of a photoanode and a photocathode comprised of NRx@TiO2 functionalized with Nile red via covalent linkage or Pd/NRx@TiO2 with additional palladium nanoparticles. The new Nile red derivatives and organic-inorganic composite electrodes were steadily prepared and well characterized using NMR, HRMS, UV-vis, FTIR, TEM, XPS, XRD and SEM. Methanol and oxygen were the products that could be detected in the liquid and gas phase. The main active species in this artificial photosynthesis system were proven using EPR spectroscopy to be hydroxy radicals releasing O2 gas via H2O2. Moreover, the carbon source of methanol was validated using a 13CO2 labeling experiment; 18O2 was determined to come from H2O using GC-MS. The optimal photoelectrocatalytic CO2 reduction was carried out using Pd/NR2@TiO2 as the working electrode yielding methanol at a rate of 106 μM h?1 cm?2 with high light quantum efficiency (Φcell = 0.95).
Nile Red-Based GPCR Ligands as Ultrasensitive Probes of the Local Lipid Microenvironment of the Receptor
Hanser, Fabien,Marsol, Claire,Valencia, Christel,Villa, Pascal,Klymchenko, Andrey S.,Bonnet, Dominique,Karpenko, Julie
, p. 651 - 660 (2021)
The local lipid microenvironment of transmembrane receptors is an essential factor in G protein coupled receptor (GPCR) signaling. However, tools are currently missing for studying endogenously expressed GPCRs in primary cells and tissues. Here, we introd
Sorption of vapors of aromatic compounds by cross-linked polymer particles containing luminophores: A spectroscopic study
Men'shikova,Moskalenko,Gribanov,Shevchenko,Faraonova,Yakimanskii,Goikhman,Loretsyan,Koshkin,Alfimov
, p. 1997 - 2005 (2010)
Monodispersed core-shell particles 290-315 nm in diameter were prepared by seed emulsion copolymerization of styrene with divinylbenzene in the presence of luminophore-containing comonomers. The capability of the particles obtained to sorb toluene vapor was shown by solid-state 1H and 13C NMR spectroscopy.
Synthesis and optical properties of covalently bound Nile Red in mesoporous silica hybrids-comparison of dye distribution of materials prepared by facile grafting and by co-condensation routes
B?rgardts, Markus,Verlinden, Kathrin,Neidhardt, Manuel,W?hrle, Tobias,Herbst, Annika,Laschat, Sabine,Janiak, Christoph,Müller, Thomas J. J.
, p. 6209 - 6222 (2016)
The fluorescence dye Nile Red (NR) can be covalently ligated to hexagonally ordered, mesoporous silica materials (MCM-41) via co-condensation and post grafting routes in order to investigate possible differences in the dye distributions. The obtained hybr
A Nile Red/BODIPY-based bimodal probe sensitive to changes in the micropolarity and microviscosity of the endoplasmic reticulum
Yang, Zhigang,He, Yanxia,Lee, Jae Hong,Chae, Weon-Sik,Ren, Wen Xiu,Lee, Joung Hae,Kang, Chulhun,Kim, Jong Seung
, p. 11672 - 11675 (2014)
We herein report a fluorescent bimodal probe (1) capable of determining ER viscosity and polarity changes using FLIM and fluorescence ratiometry, respectively; during ER stress caused by tunicamycin, the viscosity was increased from ca. 129.5 to 182.0 cP
Synthesis and characterization of bichromophoric 1-deoxyceramides as FRET probes
Izquierdo, Eduardo,Casasampere, Mireia,Fabriàs, Gemma,Abad, José Luís,Casas, Josefina,Delgado, Antonio
, p. 2456 - 2467 (2021)
The suitability as FRET probes of two bichromophoric 1-deoxydihydroceramides containing a labelled spisulosine derivative as a sphingoid base and two differently ω-labelled fluorescent palmitic acids has been evaluated. The ceramide synthase (CerS) cataly
Substituted 9-Diethylaminobenzo[ a]phenoxazin-5-ones (Nile Red Analogues): Synthesis and Photophysical Properties
Hornum, Mick,Mulberg, Mads W.,Szomek, Maria,Reinholdt, Peter,Brewer, Jonathan R.,Wüstner, Daniel,Kongsted, Jacob,Nielsen, Poul
, p. 1471 - 1488 (2021/01/13)
Nile Red is a benzo[a]phenoxazone dye containing a diethylamino substituent at the 9-position. In recent years, it has become a popular histological stain for cellular membranes and lipid droplets due to its unrivaled fluorescent properties in lipophilic environments. This makes it an attractive lead for chemical decoration to tweak its attributes and optimize it for more specialized microscopy techniques, e.g., fluorescence lifetime imaging or two-photon excited fluorescence microscopy, to which Nile Red has never been optimized. Herein, we present synthesis approaches to a series of monosubstituted Nile Red derivatives (9-diethylbenzo[a]phenoxazin-5-ones) starting from 1-naphthols or 1,3-naphthalenediols. The solvatochromic responsiveness of these fluorophores is reported with focus on how the substituents affect the absorption and emission spectra, luminosity, fluorescence lifetimes, and two-photon absorptivity. Several of the analogues emerge as strong candidates for reporting the polarity of their local environment. Specifically, the one- and two-photon excited fluorescence of Nile Red turns out to be very responsive to substitution, and the spectroscopic features can be finely tuned by judiciously introducing substituents of distinct electronic character at specific positions. This new toolkit of 9-diethylbenzo[a]phenoxazine-5-ones constitutes a step toward the next generation of optical molecular probes for advancing the understanding of lipid structures and cellular processes.
A selective Nile Red based solvatochromic probe: A study of fluorescence in LUVs and GUVs model membranes
Brunetti, Jlenia,Concilio, Simona,Di Martino, Miriam,Miele, Ylenia,Nardiello, Anna Maria,Panunzi, Barbara,Piotto, Stefano,Rossi, Federico,Sessa, Lucia
, (2021/09/04)
In this work, a membrane probe (NR18) with a Nile Red-based chromophore, a long tail of 18 carbon atoms and a zwitterionic head was synthesized. The probe is optimized to remain anchored to the phospholipid bilayer without internalizing. NR18 was fully ch
