188783-53-1

Basic information

• Product Name: Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-6-acetoxymethyl-2-(bis-benzyloxy-phosphoryloxy)-tetrahydro-pyran-3-yl ester
• Synonyms: Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-6-acetoxymethyl-2-(bis-benzyloxy-phosphoryloxy)-tetrahydro-pyran-3-yl ester
• CAS NO: 188783-53-1
• Molecular Weight: 608.536
• Mol File: 188783-53-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-6-acetoxymethyl-2-(bis-benzyloxy-phosphoryloxy)-tetrahydro-pyran-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-6-acetoxymethyl-2-(bis-benzyloxy-phosphoryloxy)-tetrahydro-pyran-3-yl ester(188783-53-1)
• EPA Substance Registry System: Acetic acid (2R,3S,4R,5R,6S)-4,5-diacetoxy-6-acetoxymethyl-2-(bis-benzyloxy-phosphoryloxy)-tetrahydro-pyran-3-yl ester(188783-53-1)

Safety Data

• Hazardous Substances Data: 188783-53-1(Hazardous Substances Data)

Upstream product

• 138514-71-3 Acetic acid (2S,3R,4R,5S)-3,5-diacetoxy-2-acetoxymethyl-6-bromo-tetrahydro-pyran-4-yl ester 
• 1623-08-1 phosphoric acid dibenzyl ester 
• 109215-53-4 penta-O-acetyl-β-L-galactopyranoside 
• 70749-17-6 1,2,3,4,6-penta-O-acetyl-α,β-L-galactose 
• 70749-15-4 2,3,4,6-tetra-O-acetyl-α-D-galactose 

Relevant articles and documents

Chemical synthesis of GDP-L-galactose and analogues

Succinct syntheses for L-galactose, 3-deoxy-L-xylo-hexose (3-deoxy-L- galactose), 6-deoxy-Lgalactopyranose (L-flucose) and 3,6-dideoxy-L-xylo- hexose (3,6-dideoxy-L-galactose) have been developed starting from commercially available L-galactono-1,4-lactone. L-Galactose and variants were then converted to the guanosine diphosphate derivatives, via the formation of the anomeric phosphates and coupling to guanosine monophosphate morpholidate.

Convenient chemoenzymatic synthesis of β-purine-diphosphate sugars (GDP-fucose-analogues)

A series of peracetylated β-sugar-1-phosphates with L-fuco configuration are efficiently prepared chemically and coupled in high yields to purine monophosphate bases via imidazolide activation. The resulting purine diphosphate sugars are deacetylated comp