188848-47-7

Basic information

• Product Name: 1H-Pyrrole-3-methanol, a-[(2,4-dichlorophenyl)methyl]-1-methyl-
• CAS NO: 188848-47-7
• Molecular Formula: C13H13Cl2NO
• Molecular Weight: 270.158
• Mol File: 188848-47-7.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-methanol, a-[(2,4-dichlorophenyl)methyl]-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-methanol, a-[(2,4-dichlorophenyl)methyl]-1-methyl-(188848-47-7)
• EPA Substance Registry System: 1H-Pyrrole-3-methanol, a-[(2,4-dichlorophenyl)methyl]-1-methyl-(188848-47-7)

Safety Data

• Hazardous Substances Data: 188848-47-7(Hazardous Substances Data)

Upstream product

• 53056-20-5 2,4-dichlorophenylacetyl chloride 
• 96-54-8 N-Methylpyrrole 
• 188848-33-1 2-(2,4-Dichloro-phenyl)-1-(1-methyl-1H-pyrrol-3-yl)-ethanone 

Relevant articles and documents

Antifungal estrogen-like imidazoles. Synthesis and antifungal activities of thienyl and 1H-pyrrolyl derivatives of 1-aryl-2-(1H-imidazol-1-yl)ethane

Reaction of arylacetyl chlorides on thiophene or pyrrole derivatives furnished 2-aryl-1-(2-thienyl)- or 2-aryl-1-(1H-pyrrol-2-yl)-1-ethanones. Reduction of ketones to the corresponding carbinols and reaction of the latter compounds with 1,1'-sulfonyldiimidazole or 1,1'-carbonyldiimidazole gave 2-thienyl- and 1H-pyrrol-2-yl-1-aryl-2-(1H-imidazol-1-yl)ethanes, respectively. The new compounds were tested in vitro against a variety of pathogenic fungi in comparison with miconazole and bifonazole. Some a 5-chloro-2-thienyl derivatives were endowed with good antifungal activity, particularly against Candida albicans and Cryptococcus neoformans.