188915-08-4Relevant articles and documents
Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1,3- dioxoperhydroimidazo[1,5-a]pyridine: A selective 5-HT(1A) receptor agonist
López-Rodríguez, María L.,Rosado, Ma. Luisa,Benhamú, Bellinda,Morcillo, Ma. José,Sanz, Antonio M.,Orensanz, Luis,Beneitez, Ma. Eugenia,Fuentes, José A.,Manzanares, Jorge
, p. 4439 - 4450 (2007/10/03)
A series of new bicyclohydantoin-arylpiperazines was prepared and evaluated for affinity at 5-HT(1A), α1, and D2 receptors. Most of the compounds showed very low affinity for D2 receptors, and most of them demonstrated mod