188937-16-8 Usage
General Description
2-Thiazoleacetic acid is a chemical compound that belongs to the thiazole group of heterocyclic compounds. It is a carboxylic acid with the molecular formula C5H5NO2S and the systematic name 2-(1,3-thiazol-2-yl)acetic acid. 2-Thiazoleacetic acid is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of polymers and other organic compounds. It is known for its versatile reactivity, making it a valuable building block in organic synthesis. The presence of the thiazole ring in 2-Thiazoleacetic acid contributes to its biological and pharmacological properties, making it a promising compound for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 188937-16-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,9,3 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 188937-16:
(8*1)+(7*8)+(6*8)+(5*9)+(4*3)+(3*7)+(2*1)+(1*6)=198
198 % 10 = 8
So 188937-16-8 is a valid CAS Registry Number.
188937-16-8Relevant articles and documents
Discovery of novel quinolinone adenosine A2B antagonists
McGuinness, Brian F.,Ho, Koc-Kan,Stauffer, Tara M.,Rokosz, Laura L.,Mannava, Neelima,Kultgen, Steven G.,Saionz, Kurt,Klon, Anthony,Chen, Weiqing,Desai, Hema,Rogers, W. Lynn,Webb, Maria,Yin, Juxing,Jiang, Yan,Li, Tailong,Yan, Hao,Jing, Konghua,Zhang, Shengting,Majumdar, Kanak Kanti,Srivastava, Vikash,Saha, Samiran
scheme or table, p. 7414 - 7420 (2011/02/23)
A novel series of quinolinone-based adenosine A2B receptor antagonists was identified via high throughput screening of an encoded combinatorial compound collection. Synthesis and assay of a series of analogs highlighted essential structural features of the initial hit. Optimization resulted in an A2B antagonist (2i) which exhibited potent activity in a cAMP accumulation assay (5.1 nM) and an IL-8 release assay (0.4 nM).
