188953-95-9Relevant academic research and scientific papers
The first example of a highly stereoselective intramolecular radical cyclisation of a cyclopentenol derivative
Jenkins, Paul R.,Wood, Andrew J.
, p. 1853 - 1856 (2007/10/03)
Silyl methylene radical cyclisation of a β-allylic cyclopentaannulated derivative of glucose leads to a single cis fused tricyclic ring system whereas the same cyclisation of the corresponding a derivative leads to a mixture of cis and trans fused products. These results can be explained by the preference for the formation of the cis fused 5,6-ring system even when this does not involve reaction from the least hindered side of the molecule.
