188990-86-5Relevant academic research and scientific papers
Acid-amide intermolecular hydrogen bonding
Wash, Paul L.,Maverick, Emily,Chiefari, John,Lightner, David A.
, p. 3802 - 3806 (1997)
A 2,2-dimethylbutynoic acid with a pyridone terminus (1) acts as its self-complement in molecular recognition to form an intermolecularly hydrogen-bonded dimer with hydrogen bonding between the amide and carboxylic acid group. The dimer is found in crystals of 1 by X-ray diffraction, in chloroform solution by 1H-NMR experiments and vapor pressure osmometry, and in the gas phase by FAB-MS.
