189011-00-5

Basic information

• Product Name: 4-(3-BROMO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE
• Synonyms: 4-(3-BROMO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE;CHEMBRDG-BB 5846891;4-(3-BROMO-4-METHOXY-PHENYL)-THIAZOL-2-YLAMINE;4-(3-bromo-4-methoxyphenyl)-1,3-thiazol-2-ylamine
• CAS NO: 189011-00-5
• Molecular Formula: C10H9BrN2OS
• Molecular Weight: 285.16
• Mol File: 189011-00-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 424.8°C at 760 mmHg
• Flash Point: 210.7°C
• Appearance: /
• Density: 1.585g/cm³
• Vapor Pressure: 2.01E-07mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 4-(3-BROMO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-BROMO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE(189011-00-5)
• EPA Substance Registry System: 4-(3-BROMO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE(189011-00-5)

Safety Data

• Hazardous Substances Data: 189011-00-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9BrN2OS/c1-14-9-3-2-6(4-7(9)11)8-5-15-10(12)13-8/h2-5H,1H3,(H2,12,13)

Upstream product

• 1515-95-3 p-ethylanisole 
• 6096-83-9 2?bromo?1?(3?bromo?4?methoxyphenyl)ethan?1?one 
• 17356-08-0 thiourea 

Relevant articles and documents

2-Amino-4-arylthiazoles through One-Pot Transformation of Alkylarenes with NBS and Thioureas

Treatment of alkylarenes with N-bromosuccinimide in a mixture of ethyl acetate and water at 60 °C, a mixture of acetonitrile and water at 80 °C, or a mixture of diethyl carbonate and water under irradiation with a tungsten lamp, followed by a reaction with thioureas or arenethioamides provided the corresponding 2-amino- 4-arylthiazoles or 2,4-diarylthiazoles in good to moderate yields, respectively, in one pot. The present reaction is an efficient one-pot transformation method of alkylarenes into 2-amino-4-arylthiazoles and 2,4-diarylthiazoles directly under mild and transition-metal-free conditions.