18908-77-5

Upstream product

• 101-81-5 Diphenylmethane 
• 1490-25-1 succinic acid monomethylester chloride 
• 63471-85-2 4-(diphenylmethylene)-4-oxobutanoic acid 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 18908-83-3 4-{4-[4-(4-{4-[4-(3-Methoxycarbonyl-propionyl)-benzyl]-benzoyl}-benzoyl)-benzyl]-phenyl}-4-oxo-butyric acid methyl ester 

Relevant academic research and scientific papers

Syntheses and antiinflammatory activity of some 6-aryl-2,3,4,5-tetrahydro-3-pyridazinones

6-Aryl-2, 3, 4, 5-tetrahydro-3-pyridazinones (2c-22c) are obtained by dehydrocyclisation of various hydrazides formed by the reaction of appropriate methyl β-aroylpropionate and hydrazine hydrate in the presence of anhydrous sodium acetate. They show promising antiinflammatory activity during their evaluation by carrageenin induced paw edema test in rats.