189130-78-7Relevant academic research and scientific papers
ARYLPIPERAZINE-CONTAINING PURINE DERIVATIVES AND USES THEREOF
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, (2012/09/22)
A novel arylpiperazine-containing purine derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating depressive disorders, are provided.
ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS
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Page/Page column 50-51, (2010/04/27)
The present invention relates to novel arylpiperazine-containing pyrrole 3-carboxamide derivatives of formula (I) or a pharmaceutically acceptable salt thereof which is useful for preventing or treating depressive disorders. The present invention also provides a method for preparing the arylpiperazine-containing pyrrole 3-carboxamide derivatives or the pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and a method for preventing or treating depressive disorders.
Oxidative Mannich reaction of N-carbobenzyloxy amines with 1,3-dicarbonyl compounds
Matsuo, Jun-Ichi,Tanaki, Yumi,Ishibashi, Hiroyuki
, p. 4371 - 4374 (2007/10/03)
(Chemical Equation Presented) Efficient carbon-carbon bond formation at the α-position of nitrogen was established by one-pot oxidative Mannich reaction of N-carbobenzyloxy (Cbz) amines with 1,3-dicarbonyl compounds using N-tert-butylbenzenesulfinimidoyl chloride as an oxidant.
