189139-52-4Relevant academic research and scientific papers
5-Lipoxygenase inhibitors: Convenient synthesis of 4-[3-(4- heterocyclylphenylthio)phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide analogues
Mano, Takashi,Stevens, Rodney W.,Okumura, Yoshiyuki,Kawai, Makoto,Okumura, Takako,Sakakibara, Minoru
, p. 2611 - 2615 (2005)
A convenient synthetic route to 4-[3-(4-heterocyclylphenylthio)phenyl]-3,4, 5,6-tetrahydro-2H-pyran-4-carboxamide analogues as 5-LO inhibitors is described. This methodology enabled rapid development of structure-activity relationships (SARs) leading to i
