18914-83-5

Basic information

• Product Name: 1-[4-fluoro-3-(trifluoromethyl)phenyl]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine
• CAS NO: 18914-83-5
• Molecular Formula: C₁₂H₁₃F₄N₅
• Molecular Weight: 303.2587
• Mol File: 18914-83-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 391.7°C at 760 mmHg
• Flash Point: 190.7°C
• Density: 1.49g/cm³
• Vapor Pressure: 2.42E-06mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 1-[4-fluoro-3-(trifluoromethyl)phenyl]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-fluoro-3-(trifluoromethyl)phenyl]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine(18914-83-5)
• EPA Substance Registry System: 1-[4-fluoro-3-(trifluoromethyl)phenyl]-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine(18914-83-5)

Safety Data

• Hazardous Substances Data: 18914-83-5(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 12 carbon atoms, 13 hydrogen atoms, 4 fluorine atoms, and 5 nitrogen atoms.

Explanation

Triazine is a heterocyclic compound consisting of a six-membered ring containing three nitrogen atoms. This compound is derived from the triazine ring system, which is a common structural motif in various pharmaceuticals and agrochemicals.

Explanation

A phenyl ring is a six-membered carbon ring with alternating single and double bonds. In this compound, the phenyl ring has a fluorine atom (F) and a trifluoromethyl group (CF3) as substituents, which can influence the compound's reactivity and properties.

Explanation

Dihydrofolate reductase is an enzyme involved in the synthesis of DNA, RNA, and proteins. By inhibiting this enzyme, the compound can disrupt the synthesis of these essential biomolecules, potentially leading to the death of rapidly dividing cells, such as cancer cells or parasites.

Explanation

Due to its ability to inhibit dihydrofolate reductase, this compound has potential applications in various fields. In the pharmaceutical industry, it can be used as an antineoplastic agent (to treat cancer) and an antimalarial agent (to treat malaria). In agriculture, it can be used as a herbicide to control the growth of unwanted plants.

Explanation

Autoimmune diseases occur when the immune system mistakenly attacks the body's own cells. The compound's ability to inhibit dihydrofolate reductase may have implications for modulating the immune system, making it a potential candidate for the treatment of autoimmune diseases. However, further research is needed to confirm its effectiveness and safety in this context.

Triazine derivative

A chemical compound derived from the triazine ring system.

Two amino groups

The presence of two amine (-NH2) functional groups in the molecule.

Fluoro and trifluoromethyl substituted phenyl ring

The presence of a phenyl ring with a fluorine atom and a trifluoromethyl group as substituents.

Inhibitor of dihydrofolate reductase

The compound inhibits the enzyme dihydrofolate reductase.

Potential applications

Pharmaceuticals, agriculture, antineoplastic, antimalarial, and herbicide.

Treatment of autoimmune diseases

The compound has been studied for its potential in treating autoimmune diseases.