189163-36-8Relevant articles and documents
Regioselective opening of epoxides to β-amido alcohols under solid-liquid PTC conditions
Albanese, Domenico,Landini, Dario,Penso, Michele
, p. 4787 - 4790 (1997)
A study on the ring opening of a number of epoxides 1 with trifluoroacetamide (2) under solid-liquid phase transfer catalysis (SL-PTC) conditions has been performed. The reaction is completely regioselective affording β-amido alcohols 3 deriving from the attack of the nucleophile to the less substituted carbon atom of the oxirane ring.