189185-92-0Relevant academic research and scientific papers
A mild and efficient procedure for ring-opening reactions of piperidine and pyrrolidine derivatives by single electron transfer photooxidation
Cocquet, Guillaume,Ferroud, Clotilde,Guy, Alain
, p. 2975 - 2984 (2007/10/03)
Various N-arylamino-1-pyrrolidines and N-arylamino-1-piperidines are selectively converted into the corresponding acyclic aminoaldehydes or amino- dialkylacetals under mild photooxidation conditions. (C) 2000 Elsevier Science Ltd.
1-substituted 1,4,5,6-tetrahydropyridazines and 1-(N-substituted)-aminopyrrolidines from hydrazines and 2,5-dimethoxytetrahydrofuran
Verardo, Giancarlo,Toniutti, Nicoletta,Giumanini, Angelo G.
, p. 3707 - 3722 (2007/10/03)
N-Substituted 1,4,5,6-tetrahydropyridazines (3) can be prepared in a one pot procedure from a hydrazine 1 and 2,5-dimethoxytetrahydrofuran (2) using NaBH4 in aqueous-THF acidic medium in fair yields, Variable amounts of two side products are also formed: hexahydropyridazines 5, likely produced by a route other than the direct reduction of 3, and 1-aminopyrrolidines 4. A direct reduction-N-reductive ethylation of3 could be achieved in AcOH with NaBH4..
