1892-92-8

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-CHLORO-4-FLUOROPHENOXY)PROPANOIC ACID is used as a phenoxyacetamide inhibitor for its ability to interfere with specific biological processes. It is particularly valuable in the development of drugs targeting various diseases and conditions, as it can modulate the activity of certain enzymes or receptors.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-(2-CHLORO-4-FLUOROPHENOXY)PROPANOIC ACID serves as a key intermediate or building block for the creation of more complex molecules. Its unique functional groups allow for further chemical reactions, leading to the formation of novel compounds with specific applications in various industries.
Used in Agrochemical Industry:
2-(2-CHLORO-4-FLUOROPHENOXY)PROPANOIC ACID is also utilized in the agrochemical industry as a component in the development of herbicides and other crop protection agents. Its ability to inhibit specific plant growth processes makes it a valuable asset in controlling unwanted vegetation and ensuring the health and productivity of crops.

InChI:InChI=1/C9H8ClFO3/c1-5(9(12)13)14-8-3-2-6(11)4-7(8)10/h2-5H,1H3,(H,12,13)

Upstream product

• 947295-84-3 C₁₁H₁₂ClFO₃ 
• 1996-41-4 2-chloro-4-fluorophenol 

Downstream Products

• 482373-01-3 C₉H₇Cl₂FO₂ 
• 1007956-28-6 N-[3,4-(methylenedioxy)benzyl]-2-(2-chloro-4-fluorophenoxy)propanamide 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of novel phenoxyacetamide inhibitors of the Pseudomonas aeruginosa type III secretion system (T3SS)

The increasing prevalence of drug-resistant bacterial infections is driving the discovery and development not only of new antibiotics, but also of inhibitors of virulence factors that are crucial for in vivo pathogenicity. One such virulence factor is the type III secretion system (T3SS), which plays a critical role in the establishment and dissemination of Pseudomonas aeruginosa infections. We have recently described the discovery and characterization of a series of inhibitors of P. aeruginosa T3SS based on a phenoxyacetamide scaffold. To better characterize the factors involved in potent T3SS inhibition, we have conducted a systematic exploration of this structure, revealing several highly responsive structure-activity relationships indicative of interaction with a specific target. Most of the structural features contributing to potency were additive, and combination of those features produced optimized inhibitors with IC50 values 1 μM.

Synthesis and herbicidal activity of α-[2-(fluoro-substituted phenoxy)propionyloxy] alkyl phosphonates

Eight of novel fluoro-substituted phosphonate derivatives were synthesized and the preliminary bioassay indicated that these compounds exhibited herbicidal activities. Copyright Taylor & Francis Group, LLC.