18920-47-3 Usage
Biological Activity
helioxanthin (ach126447) is a novel inhibitor of hbv, hcv and hsv-1 virus with ec50 values of 1 μm, 3 μm and 2 μm, respectively [1].helioxanthin has shown significant antiviral effect on hbv, hcv and hsv-1 virus in vitro with ec50 values of 1 μm, 3 μm and 2 μm, respectively. in a cell culture model, the level of hbv rna, the expression of hbv antigen and its replication were all reduced by helioxanthin. besides, helioxanthin has been exhibited to have a low cytotoxicity on both mt-223 and cem24 cell lines with id50 values of 2.5 μm and 31 μm, respectively [1].
references
[1] yeo h1, li y, fu l, zhu jl, gullen ea, dutschman ge, lee y, chung r, huang es, austin dj, cheng yc. synthesis and antiviral activity of helioxanthin analogues. j med chem. 2005 jan 27;48(2):534-46.
Check Digit Verification of cas no
The CAS Registry Mumber 18920-47-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,2 and 0 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18920-47:
(7*1)+(6*8)+(5*9)+(4*2)+(3*0)+(2*4)+(1*7)=123
123 % 10 = 3
So 18920-47-3 is a valid CAS Registry Number.