189203-98-3

Usage

Uses

Used in Pharmaceutical Industry:
Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-, is used as a precursor in the synthesis of various pharmaceutical drugs. Its unique molecular structure allows for the development of new drug candidates with potential therapeutic applications.
Used in Agricultural Chemicals:
In the agricultural industry, Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-, is used in the production of agricultural chemicals. Its properties make it suitable for the development of new pesticides or herbicides with improved efficacy and reduced environmental impact.
Used in Catalysis:
Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-, is used as a catalyst in various chemical reactions. Its organophosphorus nature allows it to facilitate reactions, improving the efficiency and selectivity of the processes.
Used as a Ligand in Transition Metal Complexes:
In the field of coordination chemistry, Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-, is used as a ligand in transition metal complexes. Its ability to form stable complexes with metal ions makes it a valuable component in the development of new catalysts and materials with specific properties and applications.
Used in Chemical Synthesis:
Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-, is used in chemical synthesis for the preparation of various organic compounds. Its reactivity and functional groups make it a useful building block for the synthesis of complex molecules with potential applications in various industries.

Upstream product

• 50777-76-9 (2-formylphenyl)(diphenyl)phosphine 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 

Downstream Products

• 1610920-62-1 [RuCl(CO)(AsPh₃)(PNS-Ph)] 
• 1610920-59-6 [RuCl(CO)(PPh₃)(PNS-Ph)] 

Relevant academic research and scientific papers

the Golden Method : Electrochemical Synthesis Is an Efficient Route to Gold Complexes

Gold compounds to be obtained by the direct electrochemical oxidation of a noble metal are reported. This achievement provides an alternative procedure to obtaining neutral gold compounds with potential medical or catalytic applications.

Ruthenium(II) complexes containing phosphino hydrazone/thiosemicarbazone ligand: An efficient catalyst for regioselective N-alkylation of amine via borrowing hydrogen methodology

In the aspect of more effective ruthenium based catalyst design, three new ruthenium(II) phosphino-hydrazone/thiosemicarbazone complexes (1–3) have been synthesized by the reactions of cis-[RuCl2(dmso)4] or [RuHCl(CO)(AsPh3)3] with deprotonated 2-(2-(diphenylphosphino)benzylidene)-2-thiophenecarboxylic acid hydrazone (PNO-Thy) or 2-(2-(diphenylphosphino)benzylidene)-4-phenyl-3-thiosemicarbazone (PNS-Ph). The structures of the complexes (2 and 3) were established by X-ray crystallography and spectroscopic methods including elemental analysis, FT-IR and NMR (1H, 13C & 31P). Single crystal XRD upshots of complexes (2 and 3) revealed a distorted octahedral geometry around the ruthenium ion with hydrazone/thiosemicarbazone acts as a monoanionic tridentate PNO/PNS donor fashion. The catalytic study of complexes 1–3 towards regioselective N-alkylation reactions of amines was completed, showing that all catalysts are active toward catalytic transformations. Notably, complex 3 was found to be very efficient catalysts toward N-alkylation of a wide range of heterocyclic amines with alcohols. This catalysis provides a clean, convenient and practical route for the direct N-alkyl amine synthesis.

Efficient and versatile catalysis of N-alkylation of heterocyclic amines with alcohols and one-pot synthesis of 2-aryl substituted benzazoles with newly designed ruthenium(ii) complexes of PNS thiosemicarbazones

Ruthenium(ii) carbonyl complexes with phosphine-functionalized PNS type thiosemicarbazone ligands [RuCl(CO)(EPh3)(L)] (1-6) (E = P or As, L = 2-(2-(diphenylphosphino)benzylidene) thiosemicarbazone (PNS-H), 2-(2-(diphenylphosphino)benzylidene)-N-methylthiosemicarbazone (PNS-Me), 2-(2-(diphenylphosphino)benzylidene)-N-phenylthiosemicarbazone (PNS-Ph)) have been synthesized and characterized by elemental analysis and spectroscopy (IR, UV-Vis, 1H, 13C, 31P-NMR) as well as ESI mass spectrometry. The molecular structures of complexes 1, 2 and 6 were identified by means of single-crystal X-ray diffraction analysis. The analysis revealed that all the complexes possess a distorted octahedral geometry with the ligand coordinating in a uni-negative tridentate PNS fashion. All the ruthenium complexes (1-6) were tested as catalyst for N-alkylation of heteroaromatic amines with alcohols. Notably, complex 2 was found to be a very efficient and versatile catalyst towards N-alkylation of a wide range of heterocyclic amines with alcohols. Complex 2 can also catalyze the direct amination of 2-nitropyridine with benzyl alcohol to the corresponding secondary amine. Furthermore, a preliminary examination of performance for N,N-dialkylation of diamine showed promising results, giving good conversion and high selectivity. In addition, N-alkylation of ortho-substituted anilines (-NH2, -OH and -SH) led to the one-pot synthesis of 2-aryl substituted benzimidazoles, benzoxazoles and benzothiazoles, also revealing the catalytic activity of complex 2. This journal is the Partner Organisations 2014.