18921-73-8

Basic information

• Product Name: N-(4-{[(2,4-diamino-5-chloroquinazolin-6-yl)methyl]amino}benzoyl)aspartic acid
• Synonyms: ASPARTIC ACID, N-(p-(((2,4-DIAMINO-5-CHLORO-6-QUINAZOLINYL)METHYL)AMINO)BENZOYL); aspartic acid, N-[4-[[(2,4-diamino-5-chloro-6-quinazolinyl)methyl]amino]benzoyl]-
• CAS NO: 18921-73-8
• Molecular Formula: C₂₀H₁₉ClN₆O₅
• Molecular Weight: 458.8551
• Mol File: 18921-73-8.mol
• Article Data: 0

Chemical Properties

• Density: 1.603g/cm³
• Refractive Index: 1.765
• CAS DataBase Reference: N-(4-{[(2,4-diamino-5-chloroquinazolin-6-yl)methyl]amino}benzoyl)aspartic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-{[(2,4-diamino-5-chloroquinazolin-6-yl)methyl]amino}benzoyl)aspartic acid(18921-73-8)
• EPA Substance Registry System: N-(4-{[(2,4-diamino-5-chloroquinazolin-6-yl)methyl]amino}benzoyl)aspartic acid(18921-73-8)

Safety Data

• Hazardous Substances Data: 18921-73-8(Hazardous Substances Data)

Usage

General Description

N-(4-{[(2,4-diamino-5-chloroquinazolin-6-yl)methyl]amino}benzoyl)aspartic acid, also known as Primaquine, is a chemical compound with molecular formula C19H21ClN6O5. It is an antimalarial medication that works by interfering with the reproduction of the parasite causing the disease. Primaquine is primarily used to treat and prevent malaria caused by Plasmodium vivax and Plasmodium ovale. It is also used in combination with other medications to treat malaria caused by Plasmodium falciparum. However, caution should be taken when using primaquine, as it can cause a condition called hemolytic anemia in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Additionally, it is important to follow dosage instructions carefully and avoid using this medication in pregnant women or individuals with known hypersensitivity to primaquine.