18926-47-1

Usage

Uses

Used in Pharmaceutical Research:
[(3-methoxybenzyl)sulfanyl]acetic acid is employed as a key compound in pharmaceutical research, attributed to its potential medicinal properties. It is often utilized in the development of new drugs and pharmaceutical products, given its unique chemical structure and functional groups.
Used in Organic Synthesis:
In the field of organic synthesis, [(3-methoxybenzyl)sulfanyl]acetic acid serves as an essential building block for the creation of more complex molecules. Its carboxylic acid functional group allows for various chemical reactions, making it a versatile component in the synthesis of a wide array of organic compounds.
Used in Antioxidant and Anti-inflammatory Applications:
Owing to its potential antioxidant and anti-inflammatory effects, [(3-methoxybenzyl)sulfanyl]acetic acid is explored for its use in the treatment of various health conditions. Its ability to combat oxidative stress and inflammation positions it as a promising candidate for therapeutic applications.
Used in the Development of New Drugs:
[(3-methoxybenzyl)sulfanyl]acetic acid's unique structure and properties make it a valuable asset in the development of novel drugs. Researchers are actively investigating its potential applications in creating new pharmaceutical products that can address a range of health issues.

Upstream product

• 874-98-6 1-bromomethyl-3-methoxybenzene 
• 68-11-1 mercaptoacetic acid 
• 824-98-6 m-methoxybenzyl chloride 

Downstream Products

• 16994-31-3 7-methoxy-1H-2-benzothiopyran-4(3H)-one 

Relevant academic research and scientific papers

Design, synthesis and evaluation of 3-substituted coumarin derivatives as anti-inflammatory agents

Coumarin moiety has garnered momentous attention especially in the design of compounds with significant biological activities. In this work, a series of 3-substituted coumarin derivatives 6a-6l were synthesized and fully characterized. Most of the compoun

Discovery of Novel 4-Arylisochromenes as Anticancer Agents Inhibiting Tubulin Polymerization

XJP-L (8), a derivative of the natural product (±)-7,8-dihydroxy-3-methylisochroman-4-one isolated from the peel of Musa sapien tum L., was found to exhibit weak inhibitory activity of tubulin polymerization (IC50 = 10.6 μM) in our previous studies. Thus, a series of 4-arylisochromene derivatives were prepared by incorporating the trimethoxyphenyl moiety into 8, among which compound (±)-19b was identified as the most potent compound with IC50 values ranging from 10 to 25 nM against a panel of cancer cell lines. Further mechanism studies demonstrated that (±)-19b disrupted the intracellular microtubule network, caused G2/M phase arrest, induced cell apoptosis, and depolarized mitochondria of K562 cells. Moreover, (±)-19b exhibited potent in vitro antivascular and in vivo antitumor activities. Notably, the R-configured enantiomer of (±)-19b, which was prepared by chiral separation, was slightly more potent than (±)-19b and was much more potent than the S-configured enantiomer in both antiproliferative and antitubulin assays. Our findings suggest that (±)-19b deserves further research as a potential antitubulin agent for the treatment of cancers.

A Study of Electronic Effects Involving Electron Deficient Nitrogen : Part IV - Schmidt & Beckmann Rearrangements of Isoquinolinones & Isothiachromanone

Schmidt and Beckmann rearrangements of isoquinolinones (1,2) and isothiachromanone (3) afford exclusively seven-membered lactams (4,5,6) resulting from aryl bond migration.No alkyl bond migration is observed as in chromanones.