189345-04-8 Usage
General Description
The chemical "(6R,7R)-7-[(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetamido]-3-[4-(1-methylpyridinium-4-yl)thiazol-2-ylsulfanyl]-3-cephem-4-carboxylate" is a complex compound with a cephalosporin core. It contains a thiazole ring and a 1,2,4-thiadiazol ring, as well as an ethoxyiminoacetamido side chain. The compound also features a pyridinium group. This molecule likely displays antibiotic properties due to its cephalosporin core, and its 1,2,4-thiadiazol ring may impart additional pharmacological activities. The unique combination of these chemical moieties could make this compound a potent and selective drug candidate for further development in the treatment of bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 189345-04-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,3,4 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 189345-04:
(8*1)+(7*8)+(6*9)+(5*3)+(4*4)+(3*5)+(2*0)+(1*4)=168
168 % 10 = 8
So 189345-04-8 is a valid CAS Registry Number.
189345-04-8Relevant articles and documents
TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: Synthesis, physicochemical and pharmacological properties
Ishikawa, Tomoyasu,Matsunaga, Nobuyuki,Tawada, Hiroyuki,Kuroda, Noritaka,Nakayama, Yutaka,Ishibashi, Yukio,Tomimoto, Mitsumi,Ikeda, Yukihiro,Tagawa, Yoshihiko,Iizawa, Yuji,Okonogi, Kenji,Hashiguchi, Shohei,Miyake, Akio
, p. 2427 - 2437 (2007/10/03)
Crystalline 1 (TAK-599) is a novel N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) cephalosporin 2a (T-91825) that has high affinity for penicillin-binding protein (PBP) 2′ (IC50; 0.90 μg/mL) and shows potent in v