189358-52-9 Usage
Physical state
Colorless liquid
Odor
Faint pleasant odor
Uses
Production of pharmaceuticals, polymers, and other industrial chemicals
Health hazards
Potentially hazardous to human health
Health effects
Can cause irritation to eyes, skin, and respiratory system upon exposure
Environmental hazards
Potential groundwater contaminant
Carcinogenicity
Classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC)
Handling and disposal
Proper handling and disposal necessary to prevent harm to human health and the environment
Check Digit Verification of cas no
The CAS Registry Mumber 189358-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,3,5 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 189358-52:
(8*1)+(7*8)+(6*9)+(5*3)+(4*5)+(3*8)+(2*5)+(1*2)=189
189 % 10 = 9
So 189358-52-9 is a valid CAS Registry Number.
189358-52-9Relevant articles and documents
Tandem use of cobalt-mediated reactions to synthesize (+)- epoxydictymene, a diterpene containing a trans-fused 5-5 ring system
Jamison, Timothy F.,Shambayati, Soroosh,Crowe, William E.,Schreiber, Stuart L.
, p. 4353 - 4363 (1997)
The diterpene (+)-epoxydictymene has been synthesized in 20 steps using the asymmetry of (R)-pulegone and several substrate-controlled diastereoselective reactions to prepare the natural product in its natural configuration. Three of the four rings were assembled with two consecutive intramolecular reactions involving dicobalt hexacarbonyl complexes of alkynes: a Lewis acid-promoted Nicholas reaction and a Pauson-Khand reaction. The construction of the strained trans-3-oxabicyclo[3.3.0]octane ring system of the natural product presented a significant challenge. To this end, several radical and anionic cyclizations were studied, the latter leading to (+)-epoxydictymene.
