189387-06-2

Upstream product

• 189387-02-8 (S)-(+)-diisopropyl 3-phenyl-1-(phthalimidooxy)propylphosphonate 
• 189386-99-0 (R)-(-)-diisopropyl 1-chloroacetoxy-3-phenylpropylphosphonate 
• 173242-86-9 (R)-(+)-diisopropyl 1-hydroxy-3-phenylpropylphosphonate 

Relevant academic research and scientific papers

Enzymes in organic chemistry - 5: First and chemo-enzymatic synthesis of α-aminooxyphosphonic acids of high enantiomeric excess

α-Acyloxyphosphonates (±)-5a and (±)-5b, derived from 3-phenylpropionaldehyde and acetaldehyde, were resolved by lipase-catalyzed enantioselective hydrolysis. Three of the four chiral, non-racemic α-hydroxyphosphonates obtained had 99% ee, the fourth 91%.