189390-29-2Relevant academic research and scientific papers
Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540)
Petitou, Maurice,Duchaussoy, Philippe,Jaurand, Guy,Gourvenec, Fran?oise,Lederman, Isidore,Strassel, Jean-Marc,Barzu, Tereza,Crépon, Bertrand,Hérault, Jean-Pascal,Lormeau, Jean-Claude,Bernat, André,Herbert, Jean-Marc
, p. 1600 - 1607 (2007/10/03)
The synthetic pentasaccharide (1) corresponding to the heparin sequence which binds to, and activates, antithrombin III (AT III) is a potent antithrombotic compound in several animal models of venous thrombosis. We describe here the preparation and the ph
