18951-77-4

Upstream product

• 533-87-9 erythro-9,10,16-trihydroxyhexadecanoic acid 
• 533-87-9 DL-threo-9RS,10RS,16-trihydroxyhexadecanoic acid 
• 1619-68-7 16-hydroxy-9-hexadecenoic acid 

Downstream Products

• 2027-46-5 threo-9.10-dihydroxy-palmitic acid 
• 1619-68-7 16-hydroxy-9-hexadecenoic acid 
• 533-87-9 erythro-9,10,16-trihydroxyhexadecanoic acid 
• 28645-51-4 (10E/Z)-oxacycloheptadec-10-en-2-one 
• 27519-02-4 (Z)-tricos-9-ene 
• 35857-62-6 trans-9-tricosene 
• 107953-39-9 3-hydroxy-9,10-isopropylidenedioxytricosane tosylate 
• 107953-26-4 (9RS,10RS)-9,10,16-triacetoxy-1-oxo-1-(2-oxo-cyclohexyl)-hexadecane 
• 66007-17-8 (S)-14-Methyl-(Z)-8-hexadecenal 
• 66007-19-0 (S,E)-(+)-14-methyl-8-hexadecenal (trogodermal) 
• 127128-02-3 (Z)-(S)-14-methylhexadec-8-ene-1-al dimethylacetal 
• 127128-03-4 (E)-(S)-14-methylhexadec-8-ene-1-al dimethylacetal 
• 533-87-9 DL-erythro-aleuritic acid 
• 109-29-5 15-hexadecanolide 

Relevant academic research and scientific papers

Preparation method of erythro-aleuritic acid

The invention provides a preparation method of erythro-aleuritic acid. The preparation method comprises the following steps: taking threo-aleuritic acid as a raw material, carrying out twice heating reflux and acid precipitation treatment to obtain erythro-aleuritic acid. Erythro-aleuritic acid is prepared through configuration conversion of threo-aleuritic acid, and a product is analyzed and confirmed by adopting characterization means such as FTIR, mass spectrum, nuclear magnetism, TG, DSC, XRD, chiral resolution, optical activity and the like. FTIR, mass spectrum, and nuclear magnetism showthat the structure of the product is consistent with that of threo-aleuritic acid; XRD, DSC and TG results show that the crystal form of threo-aleuritic acid is the same as that of the product, but the melting point of the product is higher, and the cell size is smaller; chiral resolution shows that the product is an optical isomer of aleuritic acid, that is, the product is determined to be erythro-aleuritic acid. The disclosed method can be used for effectively converting threo-aleuritic acid into erythro-aleuritic acid, and is high in conversion efficiency, high in yield of erythro-aleuritic acid and high in purity of erythro-aleuritic acid.

FT-IR Spectroscopic Studies on Aleuritic Acid

FT-IR spectra of different forms of aleuritic acid have been studied in the region 400-4000 cm-1. Difference spectra in the case of threo-aleuritic acid indicate that the purity of the acid depends on the solvent used for crystallization.

Reactions of olefinic ester derivatives of aleuritic acid with iodonium nitrate

Methyl threo-16-acetoxy-9(10)-iodo-10(9)-nitratohexadecanoate (VII) and methyl threo-16-acetoxy-9(10)-iodo-10(9)-hydroxyhexadecanoate (VIII) have been prepared by reacting methyl 16-acetoxyhexadec-cis-9-enoate (VI) which in turn has been prepared from thr