189516-46-9

Upstream product

• 107-21-1 ethylene glycol 
• 189516-45-8 (R)-1-Benzyl-2-((S)-1,2-bis-benzyloxy-ethyl)-piperidin-4-one 
• 189516-44-7 (R)-N-benzyl-2-[(S)-1,2-dibenzyloxyethyl]-5,6-dihydro-4-pyridone 

Relevant academic research and scientific papers

Asymmetric hetero Diels-Alder reaction of N-benzylimines derived from R-glyceraldehyde: A new approach to homochiral piperidine building blocks and its application to the synthesis of (2R)-4-oxopipecolic acid

The N-Benzyl imine derived from 2,3-di-O-benzyl-D-glyceraldehyde reacts with Danishefsky's diene to afford the corresponding hetero Diels-Alder adduct with a high diastereoselectivity. This compound can be transformed to enantiomerically pure (2R)-4-oxopi