189566-60-7

Basic information

• Product Name: Benzotriazole-1-carboxylic acid 4-methoxy-benzyl ester
• Synonyms: Benzotriazole-1-carboxylic acid 4-methoxy-benzyl ester
• CAS NO: 189566-60-7
• Molecular Weight: 283.287
• Mol File: 189566-60-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzotriazole-1-carboxylic acid 4-methoxy-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzotriazole-1-carboxylic acid 4-methoxy-benzyl ester(189566-60-7)
• EPA Substance Registry System: Benzotriazole-1-carboxylic acid 4-methoxy-benzyl ester(189566-60-7)

Safety Data

• Hazardous Substances Data: 189566-60-7(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 65095-13-8 1-benzotriazolecarboxylic acid chloride 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 3873-21-0 N-p-methoxybenzyloxycarbonyl-L-phenylglycine 
• 23234-86-8 N-(4-methoxybenzyloxycarbonyl)-L-phenylalanine 

Relevant articles and documents

Synthesis of 1-(t-butoxycarbonyl)benzotriazole and 1-(p-methoxybenzyloxycarbonyl)benzotriazole and their use in the protection of amino acids

Benzotriazol-1-ylcarbonyl chloride, generated from benzotriazole and phosgene, reacts with t-butyl alcohol and p-methoxybenzyl alcohol to give 1-(t-butoxycarbonyl)benzotriazole (4) and 1-(p-methoxybenzyloxycarbonyl)benzotriazole (5), respectively in good yields. The synthetic utility of ragents 4 and 5 is shown by effective amino protection in phenylalanine and phenylglycine.