189574-94-5

Basic information

• Product Name: 3-hydroxy-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one
• Synonyms: 2H-Cyclopenta[b]furan-2-one, 3,3a,4,6a-tetrahydro-3-hydroxy-
• CAS NO: 189574-94-5
• Molecular Formula: C7H8O3
• Molecular Weight: 140.13662
• Mol File: 189574-94-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-hydroxy-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one(189574-94-5)
• EPA Substance Registry System: 3-hydroxy-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one(189574-94-5)

Safety Data

• Hazardous Substances Data: 189574-94-5(Hazardous Substances Data)

Upstream product

• 542-92-7 cyclopenta-1,3-diene 
• 298-12-4 Glyoxilic acid 

Relevant articles and documents

Synthesis of radioiodinated carbocyclic cytosine analogues

The synthesis of carbocyclic analogues of normal nucleosides has grown exclusively since they have shown potential antiviral and antitumor activities. Radiolabeled cis-1-[4-(hydroxy-methyl)-cyclopent-2-enyl]-5-[124I]- iodocytosine (carbocyclic d4IC) and cis-1-[4-(hydroxy-methyl)-cyclopent-2-enyl]- 5-(2-[124I]iodovinyl)cytosine (carbocyclic d4IVC) were synthesized. The synthetic route employed Pd(0)-catalyzed coupling reaction together with organotin and exchange reaction for radioiodination as key reactions. Carbocyclic [124I]d4IC gave more than 75% radiochemical yield with greater than 95% radiochemical purity. Carbocyclic [124I]d4IVC gave more than 80% radiochemical yield with greater than 95% radiochemical purity.