1895922-77-6

Basic information

• Product Name: Boc-aminooxy-PEG4-Propargyl
• Synonyms: Boc-aminooxy-PEG4-Propargyl;t-Boc-aminooxy-PEG4-propargyl
• CAS NO: 1895922-77-6
• Molecular Formula: C16H29NO7
• Molecular Weight: 347.40396
• Mol File: 1895922-77-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Boc-aminooxy-PEG4-Propargyl(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-aminooxy-PEG4-Propargyl(1895922-77-6)
• EPA Substance Registry System: Boc-aminooxy-PEG4-Propargyl(1895922-77-6)

Safety Data

• Hazardous Substances Data: 1895922-77-6(Hazardous Substances Data)

Usage

Description

t-Boc-aminooxy-PEG4-Propargyl is a versatile click chemistry tool that features a propargyl group and a t-Boc-aminooxy group. The propargyl group is highly reactive with azide-bearing compounds or biomolecules through copper-catalyzed Click Chemistry, resulting in a stable triazole linkage. The t-Boc-aminooxy group can be deprotected under mild acidic conditions, allowing it to react with an aldehyde or ketone group to form a linkage. The hydrophilic PEG4 spacer enhances solubility in aqueous media, making this molecule a valuable component in various applications.

Uses

Used in Bioconjugation:
t-Boc-aminooxy-PEG4-Propargyl is used as a bioconjugation agent for the selective and stable attachment of biomolecules. The propargyl group enables the formation of a triazole linkage with azide-modified biomolecules, while the t-Boc-aminooxy group allows for further modification with aldehyde or ketone-containing molecules, facilitating the creation of complex bioconjugates.
Used in Drug Delivery Systems:
In the pharmaceutical industry, t-Boc-aminooxy-PEG4-Propargyl is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The hydrophilic PEG4 spacer aids in the formation of nanoparticles or other drug carriers, enhancing the overall performance of the delivery system.
Used in Materials Science:
t-Boc-aminooxy-PEG4-Propargyl is used as a building block in the development of novel materials with tailored properties. The click chemistry functionality allows for the precise and efficient assembly of complex macromolecular structures, while the PEG4 spacer contributes to the material's solubility and processability.
Used in Chemical Synthesis:
t-Boc-aminooxy-PEG4-Propargyl serves as an intermediate in the synthesis of various complex organic molecules. The unique combination of functional groups enables multiple reaction pathways, allowing chemists to construct a wide range of target molecules with high efficiency and selectivity.
Used in Diagnostics:
In the field of diagnostics, t-Boc-aminooxy-PEG4-Propargyl is used as a labeling agent for the detection and quantification of specific biomolecules. The propargyl group can be selectively reacted with azide-modified detection agents, enabling the development of sensitive and specific diagnostic assays.
Used in Research and Development:
t-Boc-aminooxy-PEG4-Propargyl is employed as a research tool in various scientific disciplines, including biology, chemistry, and materials science. Its unique properties and reactivity make it an invaluable asset for the development of new methodologies, the study of biological processes, and the design of novel materials.