18963-39-8

Basic information

• Product Name: N-phenyl-2-(phenylethynyl)benzenesulfonamide
• CAS NO: 18963-39-8
• Molecular Formula: C₂₀H₁₅NO₂S
• Molecular Weight: 333.4036
• Mol File: 18963-39-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 526°C at 760 mmHg
• Flash Point: 271.9°C
• Density: 1.31g/cm³
• Vapor Pressure: 3.74E-11mmHg at 25°C
• Refractive Index: 1.683
• CAS DataBase Reference: N-phenyl-2-(phenylethynyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-2-(phenylethynyl)benzenesulfonamide(18963-39-8)
• EPA Substance Registry System: N-phenyl-2-(phenylethynyl)benzenesulfonamide(18963-39-8)

Safety Data

• Hazardous Substances Data: 18963-39-8(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 683739-37-9 2-bromo-N-phenylbenzenesulfonamide 
• 271796-62-4 2-iodo-N-phenylbenzene-1-sulfonamide 
• 536-74-3 phenylacetylene 

Downstream Products

• 3469-20-3 2,3-diphenyl-1H-indole 

Relevant articles and documents

Switchable Divergent Synthesis in Gold-Catalyzed Difunctionalizations of o-Alkynylbenzenesulfonamides with Aryldiazonium Salts

Gold-catalyzed difunctionalizations of o-alkynylbenzenesulfonamides with aryldiazonium salts are reported herein. Upon irradiation with the blue LEDs, benzosultam products were formed via aminoarylation accompanied by the release of N2. Without irradiatio

Indole Synthesis through Sequential Electrophilic N-H and C-H Bond Activation Using Iodine(III) Reactivity

An intramolecular approach towards the regioselective construction of 2,3-diarylated indoles is reported. The reaction follows an intramolecular electrophilic N-H and C-H bond functionalization between the aniline and acetylene. This methodology employs the concept of a traceless tether to provide access to the free 2,3-diarylated indole products comprising a total of 18 examples. Hypervalent iodine reagents were identified as suitable promoters and four different protocols are provided, including stoichiometric and catalytic transformations.