189633-63-4Relevant articles and documents
A straightforward route to hydantocidin analogues with pyranose ring structure
Osz, Erzsebet,Sos, Erzsebet,Somsak, Laszlo,Szilagyi, Laszlo,Dinya, Zoltan
, p. 5813 - 5824 (2007/10/03)
Partial hydrolysis of the nitrile moiety in aeetylated 1-bromo-glycopyranosyl cyanides 1 and 9 mediated by TiCl4 gave C-(1-bromo-1-deoxy-glycopyranosyl) formamides 2 and 10 whose reaction either with AgOCN, AgSCN or KSCN in nitromethane resulted in the formation of glycopyranosylidene-spirohydantoins 3, 11 and 15 and -thiohydantoins 7 and 16. Zemplen-deacetylation gave the pyranoid epihydantocidin analogues 4 and 12, and thiohydantocidin analogues 8 and 17, respectively.