18966-58-0

Upstream product

• 245450-12-8 1-(but-3-enyl)pent-4-enylamine 
• 171858-78-9 nona-1,8-dien-5-one oxime 
• 74912-33-7 nona-1,8-dien-5-one 
• 624-83-9 methyl isocyanate 

Relevant academic research and scientific papers

Highly efficient, base-catalysed, intramolecular hydroamination of non-activated olefins

The intramolecular hydroamination of a large variety of non-activated alkenes can be efficiently catalysed by small amounts of lithium bases, providing smoothly and in high yields the corresponding five- and six-membered ring heterocycles. Fused and bridged bicyclic amines, of varying ring sizes, can be readily prepared either by a sequential hydroamination process or by a tandem, double addition reaction.

Reverse Cope Elimination Reactions. 2. Application to Synthesis

Intramolecular addition of N,N-disubstituted hydroxylamines to unactivated olefins was used to prepare an indolizine, a pyrroloisoquinoline, a 1,8-diazaspirodecane, a cyclopentapyrrole, and an isoindoline.A pyrrolizine and a 1-azabicyclo2.