189684-54-6

Basic information

• Product Name: AC-VEID-PNA
• Synonyms: CASPASE-6 SUBSTRATE II, COLORIMETRIC;CASPASE-6 SUBSTRATE (CHROMOGENIC);CASPASE 6 (MCH2) SUBSTRATE 1, CHROMOGENIC;AC-VAL-GLU-ILE-ASP-PARANITROANILIDE;AC-VAL-GLU-ILE-ASP-PNA;AC-VEID-PNA;N-ACETYL-VAL-GLU-ILE-ASP-P-NITROANILIDE;N-ACETYL-VAL-GLU-ILE-ASP-P-NITROANILIDE PNA
• CAS NO: 189684-54-6
• Molecular Formula: C28H40N6O11
• Molecular Weight: 636.65
• Product Categories: Peptide;Caspase 6Caspase;Caspase 6Enzyme Substrates;Caspase 6Caspase Inhibitors and Substrates;Caspase Substrates;Caspases;Colorimetric;Substrates;Substrates by Enzyme;Caspase/Related Products
• Mol File: 189684-54-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1086.6±65.0 °C(Predicted)
• Appearance: /powder
• Density: 1.327±0.06 g/cm3(Predicted)
• Storage Temp.: −20°C
• Solubility: DMSO: 2 mM
• PKA: 4.04±0.10(Predicted)
• CAS DataBase Reference: AC-VEID-PNA(CAS DataBase Reference)
• NIST Chemistry Reference: AC-VEID-PNA(189684-54-6)
• EPA Substance Registry System: AC-VEID-PNA(189684-54-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 189684-54-6(Hazardous Substances Data)

Usage

General Description

AC-VEID-PNA is a chemical compound that consists of the amino acid sequence AC-VEID conjugated to a peptide nucleic acid (PNA) backbone. The AC-VEID sequence is derived from the cleavage site of caspase-6, a protease involved in programmed cell death. PNA is a synthetic nucleic acid analogue that can hybridize with complementary DNA or RNA sequences. The combination of these components allows AC-VEID-PNA to potentially function as a specific inhibitor of caspase-6, which could have applications in the field of apoptosis research and drug development for diseases related to aberrant cell death processes. Further studies are needed to fully characterize the biochemical and therapeutic properties of AC-VEID-PNA.