189825-46-5Relevant academic research and scientific papers
Tetrazoles of manno- and rhamno-furanoses
Davis, Benjamin,Brandstetter, Tilmann W.,Smith, Colin,Hackett, Lucy,Winchester, Bryan G.,Fleet, George W. J.
, p. 7507 - 7510 (2007/10/02)
The synthesis of tetrazoles derived from D-mannofuranose and both enantiomers of rhamnofuranose provides the first examples of tetrazole analogues of carbohydrates in the furanose form. The D-furanotetrazoles are potential mannosidase inhibitors whereas the L-rhamnotetrazole may interfere with the biosynthesis of cell walls of mycobacteria and provide a strategy for the treatment of tuberculosis and leprosy.
