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18984-16-2

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18984-16-2 Usage

General Description

3,4-Dichloro-omega-nitrostyrene is a chemical compound characterized by the presence of nitro and styrene groups, as well as two chlorine atoms. It is frequently used in the process of organic synthesis, particularly in the creation of various pharmaceuticals and other specialty chemicals. Known for its reactivity, 3,4-dichloro-omega-nitrostyrene can engage in several different types of chemical reactions, including addition, elimination and substitution reactions. Like other nitrostyrenes, it has the capacity to participate in Michael reactions, a type of conjugate addition, which is often utilized in the preparation of crucial compounds for medicinal chemistry. Despite its wide utilization in the chemical industry, there is limited information on toxicological properties or effects on human health and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 18984-16-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,8 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18984-16:
(7*1)+(6*8)+(5*9)+(4*8)+(3*4)+(2*1)+(1*6)=152
152 % 10 = 2
So 18984-16-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5Cl2NO2/c9-7-2-1-6(5-8(7)10)3-4-11(12)13/h1-5H/b4-3+

18984-16-2 Well-known Company Product Price

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  • Alfa Aesar

  • (A15170)  3,4-Dichloro-beta-nitrostyrene, 98+%   

  • 18984-16-2

  • 5g

  • 517.0CNY

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  • Alfa Aesar

  • (A15170)  3,4-Dichloro-beta-nitrostyrene, 98+%   

  • 18984-16-2

  • 25g

  • 2029.0CNY

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  • Aldrich

  • (642150)  trans-3,4-Dichloro-β-nitrostyrene  97%

  • 18984-16-2

  • 642150-5G

  • 1,153.62CNY

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18984-16-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-DICHLORO-ω-NITROSTYRENE

1.2 Other means of identification

Product number -
Other names 3,4-DICHLORO-W-NITROSTYRENE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18984-16-2 SDS

18984-16-2Relevant articles and documents

Facile Synthesis of 1,3,5-Triarylbenzenes and 4-Aryl-NH-1,2,3-Triazoles Using Mesoporous Pd-MCM-41 as Reusable Catalyst

Saha, Arijit,Wu, Chia-Ming,Peng, Rui,Koodali, Ranjit,Banerjee, Subhash

, p. 104 - 111 (2019/01/04)

We report mesoporous nano-Pd-MCM-41 catalyzed rapid and efficient synthesis of 1,3,5-triarylbenzenes via de-nitrative cyclotrimerization of β-nitrostyrenes. All the reactions were very fast and high yielding. The Pd-MCM-41 was also very effective in catalyzing de-nitrative [3+2] cycloaddition of β-nitrostyrenes with TMSN3 to synthesize 4-aryl-NH-1,2,3-triazoles. The catalyst was reused at least up to eight times with minimum loss of catalytic activity.

Squaramide-Linked Chloramphenicol Base Hybrid Catalysts for the Asymmetric Michael Addition of 2,3-Dihydrobenzofuran-2-carboxylates to Nitroolefins

Yan, Linjie,Huang, Guanxin,Wang, Haifeng,Xiong, Fangjun,Peng, Haihui,Chen, Fener

supporting information, p. 99 - 103 (2018/01/17)

An array of hybrid catalysts incorporating a chloramphenicol base moiety linked to another chiral scaffold through a squaramide linker were developed and successfully used in the Michael addition of 2,3-dihydrobenzofuran-2-carboxylates to nitroolefins. Control experiments suggested that the hybrid catalysts were more reactive than nonhybridized bifunctional catalysts, and matching of the chirality between the two scaffolds was crucial for high reactivity and stereoselectivity. These hybrid organocatalysts could be used with a variety of substrates. At a 0.5 mol-% catalyst loading, a range of 2,3-dihydrobenzofuran-2-carboxylates derivatives bearing quaternary and tertiary stereogenic centers were obtained in high yields (up to 98 %) with excellent enantioselectivities (up to 99 % ee) and moderate diastereoselectivities (up to 8:92 dr).

17a-HYDROXYLASE/C17,20-LYASE INHIBITORS

-

Paragraph 0709, (2014/03/21)

The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4, R5, R6, A and n are as defined herein. A deuteriated derivative of the compound of Formula (I) is also provided.

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