189871-93-0Relevant articles and documents
The first hetero-bifunctionalization of the secondary face of β-cyclodextrin: Selective and efficient conversion of the A-ring of a 2A,2B-disulfonate to 2A,3A- epoxymannoside
Fukudome, Makoto,Sugimoto, Yuji,Yuan, De-Qi,Fujita, Kahee
, p. 3168 - 3170 (2008/02/12)
The A-ring of 2A,2B-O,O-di(mesitylenesulfonyl)- β-cyclodextrin was converted to 2A,3A-epoxymannoside without affecting the other sulfonylated residue, which affords the first approach to hetero-bifunctionalizati
Preparation of di-altro-β-cyclodextrins with two altrosides as the macrocyclic units through selective synthesis of regioisomers of di(2-O- mesitylenesulfonyl)-β-cyciodextrin
Ohta, Kazuko,Fujita, Kahee,Shimada, Hideaki,Ikegami, Yoshihiro,Nogami, Yasuyoshi,Koga, Toshitaka
, p. 631 - 635 (2007/10/03)
Regioisomers of di(2-O-mesitylenesulfonyl)-β-cyclodextrin 2-4 were synthesized in 3, 4 times larger yields compared to those of the reported method using dibutyltin oxide/triethylamine/p-toluenesulfonyl chloride. Regio-isomers of di-mannoepoxy-β-cyclodextrin 5-7 were prepared from 2-4 and converted to the corresponding di-altro-β-cyclodextrins (8-10) with two altrosides as macrocyclic units, respectively. Conformations of the altrose parts of di-altro-β-cyclodextrins were investigated by NMR, and the altroside was found to change its conformation depending on whether or not it is a member of the macrocyclic ring and its position in the ring.