18989-80-5 Usage
Uses
Used in Plastics Industry:
2,6-Bis(3,4-dichlorobenzylidene)cyclohexanone is used as a UV stabilizer and absorber to protect plastics from degradation caused by ultraviolet radiation, thereby extending the lifespan and maintaining the physical properties of the plastic materials.
Used in Adhesives Industry:
In the adhesives industry, 2,6-Bis(3,4-dichlorobenzylidene)cyclohexanone serves as a photostabilizer, enhancing the durability and performance of adhesives by shielding them from the damaging effects of UV exposure.
Used in Coatings Industry:
2,6-Bis(3,4-dichlorobenzylidene)cyclohexanone is utilized as a UV protectant in coatings to prevent discoloration, chalking, and loss of gloss, ensuring the long-term aesthetic and functional integrity of coated surfaces.
Used in Polymer Production:
2,6-Bis(3,4-dichlorobenzylidene)cyclohexanone is employed as a photostabilizer in the manufacturing of polymers to prolong their service life and preserve their structural and mechanical properties against UV-induced degradation.
However, it is important to note that there are concerns regarding the potential toxicity and environmental impact of 2,6-Bis(3,4-dichlorobenzylidene)cyclohexanone, which has led to regulatory restrictions on its usage in some contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 18989-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,8 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 18989-80:
(7*1)+(6*8)+(5*9)+(4*8)+(3*9)+(2*8)+(1*0)=175
175 % 10 = 5
So 18989-80-5 is a valid CAS Registry Number.
18989-80-5Relevant academic research and scientific papers
Synthesis and cytotoxic evaluation of some cyclic arylidene ketones and related oximes, oxime esters, and analogs
Dimmock,Sidhu,Chen,Li,Quail,Allen,Kao
, p. 852 - 858 (2007/10/02)
A number of arylidene derivatives of alicyclic ketones and some corresponding oximes, oxime esters, and related compounds were prepared as candidate cytotoxic agents. All of the compounds were evaluated against murine L1210 lymphoid leukemia cells. In general, cytotoxicity was greatest with the α,β-unsaturated ketones and diminished with the oximes, and the oxime esters had little or no activity in this screen. When the same compounds were examined in both the in vitro L1210 and P388 leukemia screens, in the majority of cases the L1210 cells were more sensitive to these derivatives. Over half of the compounds prepared were evaluated against approximately 55 human tumors in vitro and showed selective toxicity toward one or more groups of neoplastic diseases, particularly leukemia. Some correlations between structure and bioactivity were discerned. The cytotoxicity screening and stability studies of representative compounds suggested that the ketones, oximes, and oxime esters were stable under the conditions of bioevaluation. X-ray crystallography of four representative compounds revealed structural features associated with cytotoxicity which may be considered in the design of future candidate cytotoxins.
