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Usage

Uses

Used in Agricultural Pesticides:
(3,4-dichlorophenyl)cyanamide is used as an active ingredient in the production of agricultural pesticides for its ability to control and eliminate pests that threaten crops. Its high reactivity contributes to its effectiveness in this application.
Used in Pharmaceuticals:
In the pharmaceutical industry, (3,4-dichlorophenyl)cyanamide is utilized as a starting material or intermediate in the synthesis of various drugs, capitalizing on its chemical properties to create therapeutic agents.
Used in Antibiotics:
(3,4-dichlorophenyl)cyanamide is used as an antibiotic agent due to its inherent antibiotic properties, which can help combat bacterial infections when incorporated into medicinal formulations.
Used in Cancer Treatment Research:
(3,4-dichlorophenyl)cyanamide is used as a subject of research in cancer treatment for its potential to target and affect cancer cells. Its study aims to explore and develop its use in therapeutic applications against cancer, despite the need for extreme caution due to its toxicity.
Overall, (3,4-dichlorophenyl)cyanamide is a compound with a spectrum of potential applications across different industries; however, its use must be meticulously managed to mitigate the risks associated with its toxicity and potential health hazards.

Upstream product

• 143-33-9 sodium cyanide 
• 95-76-1 m,p-dichloroaniline 
• 506-77-4 cyanogen chloride 
• 1188410-52-7 C₇H₃Cl₂NSe 
• 506-68-3 bromocyane 

Downstream Products

• 96583-27-6 N,N'-bis-(3,4-dichloro-phenyl)-guanidine 
• 3515-05-7 Kohlensaeure-(4-chlor-2-aethoxycarbonyl-phenylester)-imid-(3,4-dichlor-phenyl-cyanamid) 
• 3305-87-1 Kohlensaeure-α-naphthylester-imid-(3,4-dichlor-phenyl-cyanamid) 
• 3305-86-0 Kohlensaeure-(2-methoxy-phenylester)-imid-(3,4-dichlor-phenyl-cyanamid) 
• 3305-85-9 Kohlensaeure-o-tolylester-imid-(3,4-dichlor-phenyl-cyanamid) 
• 3879-50-3 Kohlensaeure-(4-acetyl-phenylester)-imid-(3,4-dichlor-phenyl-cyanamid) 
• 3515-04-6 Kohlensaeure-(2-methyl-6-methoxycarbonyl-phenylester)-imid-(3,4-dichlor-phenyl-cyanamid) 
• 1224570-65-3 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-(2-pyrrolidin-1-yl-ethyl)-guanidine 
• 1276117-04-4 N-(2-pyrrolinoethyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-67-5 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-(4-pyrrolidin-1-yl-butyl)-guanidine 
• 1224570-82-4 N-(4-pyrrolinobutyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-83-5 N-(6-t-butoxycarbonylaminohexyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-68-6 {6-[N'-(3,4-dichloro-phenyl)-N''-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-guanidino]-hexyl}-carbamic acid tert-butyl ester 
• 1224570-41-5 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-methoxyguanidine 

Relevant academic research and scientific papers

Synthesis of cyanamides from isoselenocyanates promoted by recyclable ionic liquid-supported (diacetoxyiodo)benzene

One-pot synthesis of cyanamides from isoselenocyanates through deselenisation promoted by ionic liquid-supported hypervalent iodine(III) reagent 1-(4-diacetoxyiodobenzyl)-3-methylimidazolium tetrafluoroborate [dibmim BF4 was developed. This approach provided a simple, mild and environmentally benign way to construct cyanamides in good yields. Moreover, powder Se and dibmim + BF4 could be easily recycled. It was the first example of [dibmim] + [BF4- to be used as a deselenising agent.

Synthesis and antimalarial activity of 2-guanidino-4-oxoimidazoline derivatives

A series of 2-guanidino-4-oxoimidazoline (deoxo-IZ) derivatives was prepared and showed potent antimalarial activities in rodent and Rhesus models. Compound 8e, the most potent analogues of this series, is the first non-8-aminoqinoline antimalarial that demonstrated radical curative activity in non-human primate by oral route and showed causal prophylactic activity comparable to that of the commonly used clinical drugs in Rhesus monkeys infected with sporozoites of Plasmodium cynomolgi. The metabolic stability and metabolites profile indicated that the new deoxo-IZ derivatives (8) may act as prodrugs of the corresponding IZ (1 and 2) derivatives.

Preparation of aryl cyanamides from arylamines and cyanogen chloride

A process for the preparation of an aryl cyanamide comprising reacting an arylamine of the formula STR1 in which Ar is aryl, R is hydrogen or alkyl, and n is 1, 2 or 3, (excepting 2-nitroaniline, 4-nitroaniline and arylamines having a nucleophilic charact