190007-80-8

Upstream product

• 213480-19-4 (3R,4S)-3-acetoxy-1-benzyl-4-[(1S,5S)-5-benzyloxymethyl-3,3-dimethyl-2,4-dioxacyclopentane-1-yl]azetidin-2-one 
• 81028-12-8 (4S,5R)-4-benzyloxymethyl-2,2-dimethyl-1,3-dioxolane-5-carboxaldehyde 
• 190007-78-4 (3R,4S)-1-benzyl-4-[(1S,5S)-5-benzyloxymethyl-3,3-dimethyl-2,4-dioxacyclopentane-1-yl]-3-hydroxyazetidin-2-one 

Downstream Products

• 190007-83-1 (S)-2-[(S)-2-Benzylamino-2-((4S,5S)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetylamino]-3-methyl-butyric acid benzyl ester 
• 190007-82-0 (S)-2-[(S)-2-Benzylamino-2-((4S,5S)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetylamino]-3-phenyl-propionic acid benzyl ester 
• 190007-81-9 (S)-2-[(S)-2-Benzylamino-2-((4S,5S)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetylamino]-4-methyl-pentanoic acid benzyl ester 

Relevant academic research and scientific papers

Practical synthesis of α-amino acid N-carboxy anhydrides of polyhydroxylated α-amino acids from β-lactam frameworks. Model studies toward the synthesis of directly linked peptidyl nucleoside antibiotics

A straightforward method for the synthesis of polyhydroxylated α-amino acid N-carboxy anhydrides (NCAs) is described as the means by which short peptide segments comprised of a polyhydroxylated chain are easily affordable. The entire sequence lies in the

Synthetic studies towards peptidyl nucleoside antibiotics: First synthesis of a polyoxamic acid derivative enabling direct coupling with α-amino acid esters

The reaction of the Mukaiyama's aldehyde-derived N-benzyl imine with an hydroxyketene equivalent followed by exposure of the resulting α-hydroxy β-lactam to NaOCl and 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) provides a novel α-amino acid N-carboxy an