190067-61-9Relevant academic research and scientific papers
BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065
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Page/Page column 44, (2009/05/28)
The invention provides compounds of formula wherein R1, R2, R3, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1
BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066
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Page/Page column 85, (2009/06/27)
The invention provides compounds of formula wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.
Solid phase synthesis of 2-substituted benzofurans via the palladium-catalysed heteroannulation of acetylenes
Fancelli, Daniele,Fagnola, Maria Chiara,Severino, Dino,Bedeschi, Angelo
, p. 2311 - 2314 (2007/10/03)
The copper/palladium-promoted heterannulation of terminal acetylenic compounds in the presence of resin bound ortho-hydroxy aryl iodides is described. The process produces 2-substituted benzofuran derivatives in good yield and high purity.
