19008-62-9

Usage

Chemical Properties

White solid

Upstream product

• 1664-57-9 3-(3-nitrophenyl)propanoic acid 
• 5247-25-6 2-(3-nitrophenyl)acetic acid amide 

Downstream Products

• 1025819-53-7 [2-(3-Nitro-phenyl)-ethyl]-urea 
• 897373-47-6 N-(3-nitrophenethyl)-2,2,2-trifluoroacetamide 
• 273405-00-8 N-methylsulfonyl-m-nitrophenylethylamine 
• 1373423-85-8 ethyl N-[6-{[2-(3-nitrophenyl)ethyl]amino}-2-(2-pyridinyl)-4-pyrimidinyl]-β-alaninate 
• 1572937-20-2 C₁₇H₂₅N₃O₄ 

Relevant academic research and scientific papers

ENZYME MODULATORS AND TREATMENTS

Novel compounds and methods of using those compounds for the treatment of inflammatory conditions, hyperproliferative diseases, cancer, and diseases characterized by hypervascularization are provided. In a preferred embodiment, modulation of the activation state of p38 kinase protein ab1 kinase protein, bcr-ab1 kinase protein, braf kinase protein, VEGFR kinase protein, or PDGFR kinase protein comprises the step of contacting said kinase protein with the novel compounds.

Substituent effects. 14. Anomalous dissociation constants in water-organic solvent mixtures: benzylammonium ions and related systems

Thermodynamic dissociation constants in various water-organic solvent mixtures are given for benzylammonium, benzyldialkylammonium, and (2-phenylethyl)ammonium ions.Deviations from the Hammett equation (Eqn. 1) are similar to those observed for carboxylic acids, but of opposite sign.The extended Hammett equation (Eqn. 3), containing the hydrophobic constant, ?, yields good correlations.Derived secondary normal sigma values are exemplified.