19018-46-3Relevant articles and documents
Preparation of 13-Hydroxygibberellin A12-7-Aldehyde
Down, Graham J.,Lee, Michael,MacMillan, Jake,Staples, Karen S.
, p. 1103 - 1108 (2007/10/02)
7β- and 7α-Hydroxykaurenolides have been efficiently 13-hydroxylated by cultures of Rhizopus arrhizus.The products have been chemically converted into the title compound.In an alternative preparation, gibberellin A12-7-aldehyde, gibberellin A12-7-aldehyde (prepared from 7β,18-dihydroxykaurenolide), and gibberellin A12-7-aldehyde (prepared, by hydrogen-tritium exchange, from gibberellin A12-7-aldehyde), have been 13-hydroxylated by cultures of Rhizopus arrhizus to give the unlabelled and the - and -labelled title compound. 13-Hydroxylation of gibberellin A12-7-alcohol by cultures of Rhizopus arrhizus, followed by oxidation, also gave 13-hydroxygibberellin A12-7-aldehyde.